一、基本信息

姓名：陈明谅 研究员      

招生资格：硕士研究生导师 

邮箱：mlchen_gg@tio.org.cn

招生专业：海洋生物学，微生物学 

研究方向： 细胞生物学，海洋生物学

二、 研究领域：

1、海洋动物与微生物的相互作用机制研究；

2、海洋生物活性蛋白开发。

三、 目前承担的课题：

1、国家重点研发计划子课题“近海开放式养殖区病原微生物流行爆发机制及其风险预测”；

2、海洋区域示范项目子课题“南珠标准化养殖与精深加工产业链协同创新”。

四、 近期发表的文章：

1. Zhao L^#, Chen M^#, Wang X, Kang S, Xue W^*, Li Z^*. Identification of Anti-TNFα VNAR Single Domain Antibodies from Whitespotted Bambooshark ( Chiloscyllium plagiosum). Mar Drugs. 2022 Apr 29;20(5):307.

2. Lin Z^*, Wang L, Chen M^*, Zheng X, Chen J^*. Proteome and microbiota analyses characterizing dynamic coral-algae-microbe tripartite interactions under simulated rapid ocean acidification. Sci Total Environ. 2022 Mar 1;810:152266.

3. Liu G, Yang C, Liu J, Huang T, Lin L, Gu L, Li Z^*, Chen M^*. Functional characterization of a putative tumor necrosis factor superfamily member 10 in blood clam (Tegillarca granosa). Dev Comp Immunol. 2021 Nov;124:104172.

4. Liu G, Li Z, Yang M, Lin L, Liu J, Chen M*. Functional characterization of a putative lipopolysaccharide-induced TNF-alpha factor （LITAF） from blood clam Tegillarca granosa in innate immunity. Fish Shellfish Immunol. 2020 Feb;97:390-402.

5. Yang M, Chen M*, Liu G, Yang C*, Li Z*. Molecular cloning and characterization of a cDNA encoding extracellular signal-regulated kinase ( ERK) from the blood clam Tegillarca granosa. Dev Comp Immunol. 2020 Apr;105:103602.

6. Zhou Y, Liang Y, Yan Q, Zhang L, Chen D, Ruan L, Kong Y, Shi H, Chen M*, Chen J*. The draft genome of horseshoe crab Tachypleus tridentatus reveals its evolutionary scenario and well-developed innate immunity. BMC Genomics. 2020 Feb 10;21(1):137.

7. Niu S, Xia M, Chen M*, Liu X, Li Z, Xie Y, Shao Z, Zhang G*. Cytotoxic Polyketides Isolated from the Deep-Sea-Derived Fungus Penicillium chrysogenum MCCC 3A00292. Mar Drugs. 2019 Dec 5;17 (12）

8. Chen M, Wang C, Li Z, Chen J*. Involvement of JNK signaling pathway in lipopolysaccharide-induced complement C3 transcriptional activation from amphioxus Branchiostoma belcheri. Fish Shellfish Immunol. 2019 Mar;86:196-203.

9. Lin Z*, Wang L, Chen M*, Chen J*. The acute transcriptomic response of coral-algae interactions to pH fluctuation. Mar Genomics. 2018 Dec;42:32-40.

10. Liu G, Chen M*, Yu C, Wang W, Yang L, Li Z, Wang W, Chen J*. Molecular cloning, characterization and functional analysis of a putative mitogen-activated protein kinase kinase kinase 4 (MEKK4) from blood clam Tegillarca granosa. Fish Shellfish Immunol. 2017 Jul;66:372-381.

11. Lin Z, Chen M*, Dong X, Zheng X, Huang H, Xu X, Chen J*. Transcriptome profiling of Galaxea fascicularis and its endosymbiont Symbiodinium reveals chronic eutrophication tolerance pathways and metabolic mutualism between partners. Sci Rep. 2017 Feb 9;7:42100.

12. Chen M, Wang C, Wang W, Ji G, Hu B, Du M, Liu G, Li Z, Wang W, Lin X, Zheng W, Chen J*. De Novo Assembly and Characterization of Early Embryonic Transcriptome of the Horseshoe Crab Tachypleus tridentatus. PLoS One. 2016 Jan 5;11(1):e0145825.

13. Du M^#, Chen M^#, Shen H, Wang W, Li Z, Wang W, Huang J, Chen J*. CyHV-2 ORF104 activates the p38 MAPK pathway. Fish Shellfish Immunol. 2015 Oct;46(2):268-73.

14. Chen M, Chen S, Du M, Tang S, Chen M, Wang W, Yang H, Chen Q, Chen J*. Toxic effect of palladium on embryonic development of zebrafish. Aquat Toxicol. 2015 Feb;159:208-16.

五、2023年研究生培养方向

细胞生物学，海洋生物学