一、研究领域

1、基因组学、代谢组学、分子网络等工具指导的海洋微生物源活性代谢产物获取与表征，特定类型代谢产物靶向获取。

2、基于核磁共振与质谱的海洋微生物代谢组学。

二、代表性论文

ØXia, J.M.; Si, H.; Huang, X.; Chen, X.; Fu, X.; Li, G.; Lai, Q.; Li, F.; Wang, W.; Shao, Z., Metabolomics and Molecular Networking-Guided Screening of Bacillus-Derived Bioactive Compounds Against a Highly Lethal Vibrio Species. Analytical Chemistry 2024, 96, 4359−4368.

ØXia, J.M.; Xiao, W; Lin, X.; Zhou, Y.; Qiu, P.; Si, H.; Wu, X.; Niu, S.; Luo, Z.; Yang, X., Ion Mobility-Derived Collision Cross-Sections Add Extra Capability in Distinguishing Isomers and Compounds with Similar Retention Times: The Case of Aphidicolanes. Marine Drugs 2022, 20, 541.

ØXia, J.M.; Hu, X.M.; Huang, C.H.; Yu, L.B.; Xu, R.F.; Tang, X.X.*; Lin, D.H.*, Metabolic profiling of cold adaptation of a deep-sea psychrotolerant Microbacterium sediminis to prolonged low temperature under high hydrostatic pressure. Applied Microbiology and Biotechnology 2020, 104, 277-289.

ØXie, C.L.#; Xia, J.M.#; Wang, J.S.*; Lin, D.H.*; Yang, X.W.*, Metabolomic Investigations on Nesterenkonia flava Revealed Significant Differences between Marine and Terrestrial Actinomycetes. Marine Drugs 2018, 16, 356.

ØJiang, B.#; Zhang, J.#; Xia, J.M.#; Zhao, W.T.; Wu, Y.N.; Shi, M.G.; Luo, L.Z.; Zhou, H.M.; Chen, A.; Ma, H.H.; Zhao, Q.W.; Suleman, M.; Lin, F.R.; Zhou, L.; Wang, J.Y.; Zhang, Y.; He, Y.; Li, X.T.; Hung, L.-M.; Mak, T.W.; Li, Q.X.*, IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and Apoptosis Induced by Serum Starvation. Cell Reports 2017, 19, 389-400.

三、主持的代表性项目

Ø重点研发子课题，活性与靶标导向的深海药源分子发掘，2022.10-2025.12

Ø国家自然科学基金：深海真菌中aphidicolin衍生物的靶向发现，2020.01-2022.12

Ø福建省科技厅引导性项目，两株青霉属海洋真菌抗肿瘤活性物质研究，2018.04-2021.04

Ø基本科研业务费，基于串联质谱排重策略的深海微生物代谢产物馏分库活性成分发现，2022.03-2025.02

Ø重点研发子课题, 超临界流体色谱仪在海洋生物活性化合物分析及制备中的应用研究，2014.01-2017.12

四、学术兼职

Ø国际期刊Marine Drugs客座编辑